Product Name :
Periostin Recombinant Rabbit Monoclonal Antibody [JA63-40]
Predicted band size :
93 kDa
Observed band size :
85 kDa
Synonyms:
Fasciclin-I like antibody MGC119510 antibody MGC119511 antibody OSF 2 antibody OSF-2 antibody OSF2 antibody Osteoblast specific factor 2 (fasciclin I like) antibody Osteoblast specific factor 2 antibody Osteoblast specific factor antibody Osteoblast-specific factor 2 antibody 展开
Function :
Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta and alpha(V)beta integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer.19715-49-2 site Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor β 1(TGF β 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic pepride within Human Perilipin-1 aa 11-60 / 836.
Species reactivity:
Human
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JA63-40
RRID:
AB_3070511
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.1389264-32-7 Purity Aliquot store at -20℃ or -80℃.PMID:33436506 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 93 kDa
Positive control :
HaCaT cell lysate, HFF-1 cell lysate, BxPC-3 cell lysate, SH-SY5Y cell lysate, 293T cell lysate, human skin tissue lysate, human lung tissue lysate, human brain tissue lysate, human skin tissue.