Product Name :
TGF beta Receptor II Recombinant Rabbit Monoclonal Antibody [PSH01-50]
Predicted band size :
65 kDa
Observed band size :
65-80 kDa
Synonyms:
AAT3 antibody FAA3 antibody LDS1B antibody LDS2 antibody LDS2B antibody MFS2 antibody RIIC antibody TAAD2 antibody TbetaR II antibody TbetaR-II antibody 展开
Function :
Transforming growth factor, beta receptor II (70/80kDa) is a TGF beta receptor. TGFBR2 is its human gene. It is a tumor suppressor gene. This gene encodes a member of the serine/threonine protein kinase family and the TGFB receptor subfamily.2-Chloro-5-nitropyrazine Formula The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta.Buy5-Ethynyluridine This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler–Weber–Rendu syndrome, and the development of various types of tumors.PMID:33535005 At least 73 disease-causing mutations in this gene have been discovered. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within human TGF beta Receptor II aa 23-166 (Extracellular).
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
PSH01-50
RRID:
AB_3072806
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 65 kDa
Positive control :
HepG2 cell lysate, A549 cell lysate, HT-29 cell lysate.