Product Name :
beta Amyloid 1-40 Recombinant Rabbit Monoclonal Antibody [PSH05-86]
Predicted band size :
4 kDa
Observed band size :
4 kDa
Synonyms:
A4 antibody A4_HUMAN antibody AAA antibody ABETA antibody ABPP antibody AICD-50 antibody AICD-57 antibody AICD-59 antibody AID(50) antibody AID(57) antibody 展开
Function :
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides.Buy6-Chloroquinoline-2-carboxylic acid Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).2,4,6-Trichloro-5-cyanopyrimidine site Multiple transcript variants encoding several different isoforms have been found for this gene.PMID:33461880
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human beta Amyloid 1-40 peptide.
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P, IF-Tissue
Coupling :
unconjugated
Clone number:
PSH05-86
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 4 kDa
Positive control :
APP/PS1, 6-month mouse of AD brain tissue.